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Whole-genome ancestry of an Old Kingdom Egyptian

PRJEB88328 Original Paper / DOI2025-07-021 samples (study)

AI interpretationAI-generated

First whole genome of an Old Kingdom Egyptian reveals mixed ancestry.

Researchers sequenced a 2X whole genome from an adult male buried in a ceramic pot at Nuwayrat, Egypt, dated to 2855-2570 BCE. Most of his ancestry matches North African Neolithic groups, but about 20% comes from the eastern Fertile Crescent, including Mesopotamia, similar to ancient Anatolian and Levantine populations. This suggests that Egypt's contacts with the east involved human migration, not just trade in goods and ideas.

Sample interpretation

The site_samples count is 1, meaning this study analyzed a single individual. His Y-chromosome haplogroup is E-FT388828, a lineage common in North Africa. His mitochondrial haplogroup is I9. The cultural context is Dynastic/Old Kingdom. This is the only sample from this site, so interpretations are based on one genome.

For genealogy enthusiasts

For ancestry enthusiasts, this genome shows that early Egyptians were not isolated. If you have North African or Middle Eastern ancestry, you may carry signals from similar ancient mixtures. It highlights how ancient human migration shaped Egypt's population.

Abstract

Ancient Egyptian society flourished for millennia, reaching its peak during the Dynastic period (~3,150-30 BCE). However, due to poor DNA preservation, questions about regional interconnectivity through time have not been addressed as whole genome sequencing has not been possible to date. Here, we sequenced a 2X coverage whole genome from an adult male excavated at Nuwayrat (Nuerat, نويرات). Radiocarbon-dated to 2,855-2,570 cal BCE, he lived a few centuries after Egyptian unification, bridging the Early Dynastic and Old Kingdom periods. The body was interred in a ceramic pot within a rock-cut tomb, potentially contributing to the DNA preservation. Most of his genome is best represented by North African Neolithic ancestry, among currently available sources. Yet, ~20% of his genetic ancestry can be traced to genomes representing the eastern Fertile Crescent, including Mesopotamia and surrounding regions. This genetic affinity is similar to ancestry appearing also in Anatolia and the Levant during the Neolithic and Bronze Age. Although more genomes are needed to fully understand the genomic diversity of early Egyptians, our results indicate that contacts between Egypt and the eastern Fertile Crescent were not limited to objects and imagery (e.g. domesticated animals and plants, writing systems), but also encompassed human migration.

Samples & Data on TheYtree

1samples on site
1Y haplogroup resolved

Paternal (Y-DNA) Haplogroups

HaplogroupSamples
E-FT388828 1

Maternal (mtDNA) Haplogroups

Sample Highlights More samples →

SampleY-DNAmtDNACulture / Period
NUE001 E-FT388828 I9 Dynastic / Old kingdom· 2,855-2,570 cal BCE