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Single-cell karyotype sequencing data of rectal cancer organoids before and after radiation

PRJNA1015247 2023-10-1216 samples (study)

Abstract

More than half of all cancer patients receive radiation therapy, but resistance is commonly observed. Currently, it is unknown if resistance to radiation therapy is acquired, inherently present, or a combination of both. This SRA contains single-cell karyotype sequencing data of rectal cancer organoids before and after 10 Gy of radiation that allows the analysis of subclonal dynamics in response to radiation therapy.

Samples & Data on TheYtree

16samples on site
4Y haplogroup resolved

Paternal (Y-DNA) Haplogroups

HaplogroupSamples
I-S19763 1
R-A7905 1
R-PF6538 1
I-S24121 1

Maternal (mtDNA) Haplogroups

Sample Highlights More samples →

SampleY-DNAmtDNACulture / Period
SCC-scKaryo-UMC-KRA-005 R-PF6538 H4a1a1a1a
SCC-scKaryo-UMC-KRA-006 R-A7905 H4a1a1a1a
SCC-scKaryo-UMC-KRA-022 I-S19763 W1-T119C
SCC-scKaryo-UMC-KRA-023 I-S24121 W1-T119C