DNA论文
2026-10-17
患有独眼畸形和13号染色体三体的古代个体的基因组
Cyclopia, the most severe craniofacial manifestation of alobar holoprosencephaly, is a rare and lethal congenital condition. While trisomy 13 is a maj…
2022-10-01
Ancient Components and Recent Expansion in the Eurasian Heartland: Insights into the Revised Phylogeny of Y-Chromosomes from Central Asia
欧亚腹地的古代成分和近期扩张：对中亚 Y 染色体系统发育的见解
In the past two decades, studies of Y chromosomal single nucleotide polymorphisms (Y-SNPs) and short tandem repeats (Y-STRs) have shed light on the de…
2026-07-07
中亚基因组多样性计划的全基因组测序试点揭示了独特的历史、适应和基因渗入
Central Asians are underrepresented in genomic research, limiting insights into their genetic history and disease risk. We established the Central Asi…
2026-10-16
2026-10-14
基因组学视角揭示黑龙江流域人口的寒冷适应性和种群历史
Human adaptation to extreme cold has been studied predominantly in Arctic populations, leaving the genetic basis of cold resilience in non-Arctic high…
2017-06-17
胰腺导管腺癌和胰腺腺鳞癌的测序
In this study, whole genome sequencing and whole exome sequencing were performed to detected the genomic features of the pancreatic adenosquamous carc…
2016-07-23
囊性纤维化患者呼吸道急性加重的诊断
Respiratory samples collected at the Academisch Medisch Centrum from cystic fibrosis patients were analysed by next generation sequencing (16S amplico…
2023-10-12
直肠癌类器官放射治疗前后的单细胞核型测序数据
More than half of all cancer patients receive radiation therapy, but resistance is commonly observed. Currently, it is unknown if resistance to radiat…
2026-10-10
基因组学揭示黄河中下游流域数千年来的遗传连续性和跨区域基因混合。
The middle and lower Yellow River regions were crucial for early agricultural development and the emergence of complex societies in East Asia, yet the…
2022-11-29
台湾阿美族和雅美族原住民及其与东亚和太平洋地区人群的遗传关系
2022-11-30
来自中世纪德国犹太人的全基因组数据表明德系犹太人创始人事件早于 14 世纪
2023-08-09
从草原个体到库库特尼—特里波利文化人群的基因流表明长期接触和逐渐混合
2023-08-10
对匈牙利西部青铜时代社区的跨学科分析揭示了复杂的人口历史
2024-12-20
东马格里布新石器时代采集者祖先的高度连续性
地中海地区的古代 DNA 揭示了与粮食生产经济体扩张相关的远距离联系和人口转变。然而，与欧洲不同，北非这一关键转变的基因数据有限，而且只有来自最西部的马格里布（摩洛哥）的基因数据可用。在这里，我们展示了阿尔及利亚和突尼斯从晚石器时代 (LSA) 到新石器时代的九个人的全基因组数据。最早的个体与西马格…
2025-02-20
古代线粒体基因组揭示了新石器时代晚期中国中原地区人群与母系遗传多样性的相互作用
中原地区是中国最早的粟、黍驯化中心之一，孕育了丰富的考古学文化，在新石器时代与周边人群有着广泛的互动。然而，有限的基因组研究阻碍了人们对这一时期母系遗传结构和人口扩张历史的清晰认识。本文报告了来自河南龙山文化时期阎寨遗址人群的12个完整线粒体基因组，揭示了较高的母系遗传多样性。这些个体与黄河流域古代…
2020-11-05
2023-03-01
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