We present a comprehensive genetic investigation of Late Neolithic and Early Copper Age populations living in the Carpathian Basin, leveraging whole g…
Cyclopia, the most severe craniofacial manifestation of alobar holoprosencephaly, is a rare and lethal congenital condition. While trisomy 13 is a maj…
Central Asians are underrepresented in genomic research, limiting insights into their genetic history and disease risk. We established the Central Asi…
In this study, whole genome sequencing and whole exome sequencing were performed to detected the genomic features of the pancreatic adenosquamous carc…
Respiratory samples collected at the Academisch Medisch Centrum from cystic fibrosis patients were analysed by next generation sequencing (16S amplico…
More than half of all cancer patients receive radiation therapy, but resistance is commonly observed. Currently, it is unknown if resistance to radiat…
The middle and lower Yellow River regions were crucial for early agricultural development and the emergence of complex societies in East Asia, yet the…
The Early Bronze Age in Central Europe (~ 2200–1600 BC) saw the emergence of hierarchical social organisation, expressed most visibly in large burial …
During the medieval period, hundreds of thousands of Europeans migrated to the Near East to take part in the Crusades, and many of them settled in the…
The border region, which lies between different regimes, is highly regarded because of its diverse population, dietary habits, and living conditions. …
The transition from the Late Neolithic to the Bronze Age has witnessed important population and societal changes in western Europe.1 These include mas…
This project compares terminal trimming, mapDamage2 base-quality rescaling and bamRefine known-SNP masking in matched full uracil-DNA glycosylase-trea…
Studies of ancient DNA from cemeteries provide valuable insights into early human societies, and have strongly indicated patrilocality. Here, we analy…
The Yan Mountain Region (YMR), a transition zone between the Mongolian Plateau and northern China, played a pivotal yet understudied role in shaping t…
We generated genome-wide and proteome data from eight individuals from four archaeological sites in the Middle Yellow River dating from the Middle Neo…